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TitleChimeric and Non-Chimeric Foldamer Mimics of the CHR Segment of HIV Protein gp41: Evidence for the Importance of a Large Binding Interface in Six-Helix Bundle Formation
Journal, issue, pagesTo be Published
Publish dateJul 26, 2010 (structure data deposition date)
AuthorsHorne, W.S. / Johnson, L.M. / Gellman, S.H.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.35 - 3 Å
Structure data

PDB-3o3y:
A chimeric alpha+alpha/beta peptide based on the CHR domain sequence of gp41
Method: X-RAY DIFFRACTION / Resolution: 1.35 Å

PDB-3o42:
Complex of an alpha/beta-peptide based on the gp41 CHR domain bound to gp41-5
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

ChemComp-IPA:
ISOPROPYL ALCOHOL

Source
  • artificial gene (others)
KeywordsVIRAL PROTEIN / HIV fusion inhibitor / HIV gp41 / mixed alpha-residue / beta-residue backbone / mixed alpha-peptide / beta-peptide backbone

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