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TitleStructure of L1196M,G1269A Double Mutant Anaplastic Lymphoma Kinase in Complex with Crizotinib
Journal, issue, pagesTo be Published
Publish dateMar 22, 2012 (structure data deposition date)
AuthorsMctigue, M. / Deng, Y. / Liu, W. / Brooun, A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.85 Å
Structure data

PDB-4ans:
Structure of L1196M,G1269A Double Mutant Anaplastic Lymphoma Kinase in Complex with Crizotinib
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-VGH:
3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine / medication, anticancer*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE

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