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Structure paper

TitleThe mitochondrial methylation potential gates mitoribosome assembly
Journal, issue, pagesTo Be Published
Publish dateNov 8, 2024 (structure data deposition date)
AuthorsGlasgow R / Singh V / Pena-Perez L / Wilhalm A / Moedas MF / Moore D / Rosenberger FA / Li X / Atanassov I / Saba M ...Glasgow R / Singh V / Pena-Perez L / Wilhalm A / Moedas MF / Moore D / Rosenberger FA / Li X / Atanassov I / Saba M / Cipullo M / Rorbach J / Wedell A / Freyer C / Amunts A / Wredenberg A
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.91 - 7.42 Å
Structure data

52048

9hcg

EMDB-52048, PDB-9hcg:
Mouse mitoribosome large subunit assembly intermediate bound to NSUN4, METRF4, MRM2, GTPBP7 and MALSU1-L0R8F8-mt-ACP complex, State D (SAMC knock-out)
Method: EM (single particle) / Resolution: 2.91 Å

EMDB-52408: Mouse mitochondrial large subunit assembly intermediate in complex with MRM2 dimer with uL16m bound (SAMC Knock-out)
Method: EM (single particle) / Resolution: 7.42 Å

EMDB-52430: Mouse mitoribosome large subunit assembly intermediate bound to NSUN4, MTERF4 and the MALSU1-L0R8F8-mtACP complex, State C2 (SAMC knock-out)
Method: EM (single particle) / Resolution: 3.13 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ZN:
Unknown entry

ChemComp-FES:
FE2/S2 (INORGANIC) CLUSTER

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsRIBOSOME / mitochondria / large subunit / assembly intermediate

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