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IF

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Structure paper

TitleMutations in myosin VI that cause a loss of coordination between heads provide insights into the structural changes underlying force generation and the importance of gating
Journal, issue, pagesTo be Published
Publish dateJan 16, 2012 (structure data deposition date)
AuthorsSong, L. / Pylypenko, O. / Yang, Z. / Houdusse, A. / Sweeney, L.H.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.95 - 2.6 Å
Structure data

PDB-4dbp:
Myosin VI nucleotide-free (MDINSERT2) D179Y crystal structure
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-4dbq:
MYOSIN VI D179Y (MD-INSERT2-CAM, DELTA-INSERT1) post-rigor state
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-4dbr:
Myosin VI D179Y (MD) pre-powerstroke state
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-TBU:
TERTIARY-BUTYL ALCOHOL

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-IPA:
ISOPROPYL ALCOHOL / alkaloid*YM

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-BEF:
BERYLLIUM TRIFLUORIDE ION

ChemComp-MG:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-VO4:
VANADATE ION

Source
  • sus scrofa (pig)
  • drosophila melanogaster (fruit fly)
Keywordsmotor protein/Calcium binding protein / motor protein / motor protein-Calcium binding protein complex / calcium binding protein

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