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Structure paper

Title1TEL Fusions Outperform 2TEL and 3TEL Fusions in Controlled Comparisons
Journal, issue, pagesTo Be Published
Publish dateJul 18, 2024 (structure data deposition date)
AuthorsSamarawickrama, P. / Ludlow, K. / Probst, R. / Abiodun, W. / Averett, J. / Hansen, D. / Doukov, T. / Moody, J.D.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.19 - 2.4 Å
Structure data

PDB-9cpl:
The ubiquitin-associated domain of human thirty-eight negative kinase 1, fused to the 2TEL crystallization chaperone via a 2-glycine linker
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-9doc:
The von Willebrand factor A domain of human capillary morphogenesis gene II, flexibly fused to the 1TEL crystallization chaperone, Thr-Val linker variant, at 1.2 Angstrom resolution
Method: X-RAY DIFFRACTION / Resolution: 1.19 Å

PDB-9o0h:
The ubiquitin-associated domain of human thirty-eight negative kinase 1, fused to the 3TEL crystallization chaperone via a 2-glycine linker
Method: X-RAY DIFFRACTION / Resolution: 2.24 Å

Chemicals

ChemComp-FMT:
FORMIC ACID

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

ChemComp-PO4:
PHOSPHATE ION

ChemComp-MG:
Unknown entry

ChemComp-NA:
Unknown entry

Source
  • homo sapiens (human)
KeywordsONCOPROTEIN / TELSAM / 2TEL / Pointed Domain / ETS / TEL / TNK1 / UBA Domain / Broken Periodicity / PEPTIDE BINDING PROTEIN / 1TEL / Sterile Alpha Motif domain / CMG2 / vWA Domain / Anthrax toxin receptor 2 / 3TEL

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