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Structure paper

TitleStructure of Agonist-Bound Estrogen Receptor Beta Lbd in Complex with Lxxll Motif from Ncoa5
Journal, issue, pagesTo be Published
Publish dateOct 17, 2006 (structure data deposition date)
AuthorsPike, A.C.W. / Brzozowski, A.M. / Hubbard, R.E. / Walton, J. / Bonn, T. / Thorsell, A.-G. / Engstrom, O. / Ljunggren, J. / Gustaffson, J.-A. / Carlquist, M.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.8 - 2.1 Å
Structure data

PDB-2j7x:
STRUCTURE OF ESTRADIOL-BOUND ESTROGEN RECEPTOR BETA LBD IN COMPLEX WITH LXXLL MOTIF FROM NCOA5
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-2j7y:
STRUCTURE OF 17-EPIESTRIOL-BOUND ESTROGEN RECEPTOR BETA LBD IN COMPLEX WITH LXXLL MOTIF FROM NCOA5
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-EST:
ESTRADIOL / hormone*YM

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-SO4:
SULFATE ION

ChemComp-BCT:
BICARBONATE ION / pH buffer*YM

ChemComp-HOH:
WATER

ChemComp-E3O:
(16ALPHA,17ALPHA)-ESTRA-1,3,5(10)-TRIENE-3,16,17-TRIOL

Source
  • rattus norvegicus (Norway rat)
  • homo sapiens (human)
KeywordsTRANSCRIPTION / ZINC-FINGER / NUCLEAR RECEPTOR / PHOSPHORYLATION / STEROID-BINDING / GLYCOPROTEIN / TRANSCRIPTION REGULATION / RECEPTOR / ACTIVATOR / REPRESSOR / TRANSCRIPTION FACTOR / NUCLEAR PROTEIN / COACTIVATOR / COREPRESSOR / DNA-BINDING / METAL-BINDING / LIPID-BINDING

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