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TitleSingle step syntheses of (1S)-aryl-tetrahydroisoquinolines by norcoclaurine synthases
Journal, issue, pagesCommun Chem, Year 2020
Publish dateJun 2, 2020 (structure data deposition date)
AuthorsRoddan, R. / Sula, A. / Mendez-Sanchez, D. / Subrizi, F. / Lichman, B.R. / Broomfield, J. / Richter, M. / Andexer, J.N. / Ward, J.M. / Keep, N.H. / Hailes, H.C.
External linksCommun Chem / Search PubMed
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-6z82:
Thalictrum flavumn Norcoclaurine synthase point mutant in complex with a transition state analoge
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-QBW:
4-[2-[(phenylmethyl)amino]ethyl]benzene-1,2-diol

ChemComp-HOH:
WATER

Source
  • thalictrum flavum subsp. glaucum (plant)
KeywordsLYASE / PICTET SPENGLER CONDENSATION / DOPAMINE

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