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TitleCrystal structure of human alphaER-LBD in complex with GRIP peptide and 16alpha-hydroxyestrone
Journal, issue, pagesTo be Published
Publish dateMay 28, 2009 (structure data deposition date)
AuthorsRajan, S.S. / Kim, Y. / Vanek, K. / Joachimiak, A. / Greene, G.L.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-3hlv:
Crystal structure of human Estrogen Receptor Alpha Ligand-Binding Domain in complex with a Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide and 16-alpha-hydroxy-estrone ((8S,9R,13S,14R,16R)-3,16-dihydroxy-13-methyl-7,8,9,11,12,14,15, 16-octahydro-6H-cyclopenta[a]phenanthren-17-one
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-J2Z:
(9beta,13alpha,16beta)-3,16-dihydroxyestra-1,3,5(10)-trien-17-one

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / estrogen receptor / LBD / GRIP peptide / hydroxy-estrone / Alternative splicing / DNA-binding / Glycoprotein / Lipid-binding / Metal-binding / Nucleus / Phosphoprotein / Polymorphism / Receptor / Steroid-binding / Transcription regulation / Zinc / Zinc-finger / Activator / HORMONE / NUCLEAR RECEPTOR

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