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Structure paper

TitleThe cocrystal structure of FGFR2 bound with compound 14 harboring 5H-pyrrolo[2,3-b]pyrazine scaffold
Journal, issue, pagesTo be published
Publish dateAug 15, 2018 (structure data deposition date)
AuthorsXiong, B.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.95 Å
Structure data

PDB-6agx:
The cocrystal structure of FGFR2 bound with compound 14 harboring 5H-pyrrolo[2,3-b]pyrazine scaffold
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

Chemicals

ChemComp-9WX:
ethyl [4-({3-[2-(3,5-dimethoxyphenyl)ethyl]-5H-pyrrolo[2,3-b]pyrazin-5-yl}sulfonyl)-1H-imidazol-1-yl]acetate

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/INHIBITOR / Tyrosine-protein kinase / TRANSFERASE-INHIBITOR complex

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