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TitleCrystal structure of Human p38 alpha MAPK in Complex with MW01-8 -066WH
Journal, issue, pagesTo Be Published
Publish dateApr 8, 2025 (structure data deposition date)
AuthorsBrunzelle, J.S. / Shuvalova, L. / Roy, S.M. / Watterson, D.M.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.27 Å
Structure data

PDB-9o4l:
Crystal structure of Human p38 alpha MAPK in Complex with MW01-8 -066WH
Method: X-RAY DIFFRACTION / Resolution: 2.27 Å

Chemicals

ChemComp-GG5:
4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE


PDB Unreleased entry

PDB-1b8b: Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / SERINE/THREONINE-PROTEIN KINASE / PROTEIN KINASE DOMAIN / TRANSFERASE / ATP BINDING / PHOSPHORYLATION / CYTOSOL / TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX

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