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Structure paper

TitleCrystal structure of human Haspin (GSG2) kinase bound to MU1959
Journal, issue, pagesTo Be Published
Publish dateJun 5, 2024 (structure data deposition date)
AuthorsKraemer, A. / Paruch, K. / Knapp, S. / Structural Genomics Consortium (SGC)
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.85 - 1.91 Å
Structure data

PDB-9flq:
Crystal structure of human Haspin (GSG2) kinase bound to MU1959
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

PDB-9flr:
Crystal structure of human Haspin (GSG2) kinase bound to MU1963
Method: X-RAY DIFFRACTION / Resolution: 1.91 Å

Chemicals

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-NA:
Unknown entry

PDB-1idd:
ISOCITRATE DEHYDROGENASE Y160F MUTANT APO ENZYME

ChemComp-NI:
NICKEL (II) ION

ChemComp-HOH:
WATER

PDB-1ide:
ISOCITRATE DEHYDROGENASE Y160F MUTANT STEADY-STATE INTERMEDIATE COMPLEX (LAUE DETERMINATION)

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Haspin / Kinase / Inhibitor

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