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TitleTRIM21 PrySpry domain bound to an enhanced PRLX-93936 analog
Journal, issue, pagesTo Be Published
Publish dateNov 30, 2024 (structure data deposition date)
AuthorsHinshaw, S.M. / Corsello, S.M. / Yuan, L. / Lu, J. / Martinez, M. / Gray, N.S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-9ek5:
TRIM21 PrySpry domain bound to an enhanced PRLX-93936 analog
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

PDB-1bld:
BASIC FIBROBLAST GROWTH FACTOR (FGF-2) MUTANT WITH CYS 78 REPLACED BY SER AND CYS 96 REPLACED BY SER, NMR

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / TRIM21 / ubiquitin / ubiquitin ligase / small molecule / protein degradation / innate immunity / cancer / therapeutics

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