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Structure paper

TitleStructural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases
Journal, issue, pagesTo be Published
Publish dateSep 3, 2008 (structure data deposition date)
AuthorsMac Sweeney, A. / Parrado, S.G. / Vinzenz, D. / Bernardi, A. / Hein, A. / Bodendorf, U. / Erbel, P. / Logel, C. / Gerhartz, B.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.25 - 1.4 Å
Structure data

PDB-3edg:
Crystal structure of bone morphogenetic protein 1 protease domain
Method: X-RAY DIFFRACTION / Resolution: 1.27 Å

PDB-3edh:
Crystal structure of bone morphogenetic protein 1 protease domain in complex with partially bound DMSO
Method: X-RAY DIFFRACTION / Resolution: 1.25 Å

PDB-3edi:
Crystal structure of tolloid-like protease 1 (TLL-1) protease domain
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-ACE:
ACETYL GROUP

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
KeywordsHYDROLASE / vicinal disulfide / Alternative splicing / Calcium / Chondrogenesis / Cleavage on pair of basic residues / Cytokine / Developmental protein / Differentiation / EGF-like domain / Glycoprotein / Growth factor / Metal-binding / Metalloprotease / Osteogenesis / Polymorphism / Protease / Zinc / Zymogen / disordered cysteine-rich loop / Secreted

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