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TitleDrug Resistant HIV-1 Protease (L10F, M46I, I47V, I50V, F53L, L63P, I72V, G73S, V82I, I85V) in Complex with DRV
Journal, issue, pagesTo Be Published
Publish dateMar 31, 2021 (structure data deposition date)
AuthorsLockbaum, G.J. / Schiffer, C.A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-7mar:
Drug Resistant HIV-1 Protease (L10F, M46I, I47V, I50V, F53L, L63P, I72V, G73S, V82I, I85V) in Complex with DRV
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-017:
(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE / medication, antiretroviral*YM

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus type 1 group m subtype b
KeywordsHYDROLASE/HYDROLASE INHIBITOR / drug resistance / HYDROLASE-HYDROLASE INHIBITOR complex

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