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TitleCrystal structure of LpxC from Pseudomonas aeruginosa in complex with PF-5081090
Journal, issue, pagesto be published
Publish dateFeb 2, 2017 (structure data deposition date)
AuthorsPhan, J.N. / Delker, S.L. / Lorimer, D.D. / Edwards, T.E.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-5upg:
Crystal structure of LpxC from Pseudomonas aeruginosa in complex with PF-5081090
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-8GJ:
(2R)-4-[4-(2-fluoro-4-methoxyphenyl)-2-oxopyridin-1(2H)-yl]-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide

ChemComp-ZN:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1) (bacteria)
KeywordsHYDROLASE / SSGCID / LpxC / UDP-3-O-acyl-N-acetylglucosamine deacetylase / PF-5081090 / lipid A biosynthesis / Structural Genomics / Seattle Structural Genomics Center for Infectious Disease

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