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TitleCrystal Structure of Human Death Associated Protein Kinase 3 (DAPK3) in Complex with an Imidazo-Pyridazine Ligand.
Journal, issue, pagesTo be Published
Publish dateDec 20, 2007 (structure data deposition date)
AuthorsFilippakopoulos, P. / Rellos, P. / Fedorov, O. / Niesen, F. / Pike, A.C.W. / Pilka, E.S. / von Delft, F. / Arrowsmith, C.H. / Edwards, A.M. / Weigelt, J. / Knapp, S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.75 Å
Structure data

PDB-3bqr:
Crystal structure of human death associated protein kinase 3 (DAPK3) in complex with an imidazo-pyridazine ligand
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-4RB:
4-(6-{[(1R)-1-(hydroxymethyl)propyl]amino}imidazo[1,2-b]pyridazin-3-yl)benzoic acid

ChemComp-PGO:
S-1,2-PROPANEDIOL

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Death Associated Kinase / DAPK3 / ZIP kinase / ZIPK / DAP kinase 3 / DAP like kinase / Dlk / Structural Genomics Consortium / SGC / Apoptosis / ATP-binding / Chromatin regulator / Nucleotide-binding / Nucleus / Serine/threonine-protein kinase

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