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TitleCrystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-585
Journal, issue, pagesTo Be Published
Publish dateJan 7, 2021 (structure data deposition date)
AuthorsKarim, M.R. / Schonbrunn, E.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.35 Å
Structure data

PDB-7lb1:
Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-585
Method: X-RAY DIFFRACTION / Resolution: 1.35 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-XWV:
5-{4-[(3R)-3-methylmorpholin-4-yl]-6-[1-(S-methylsulfonimidoyl)cyclopropyl]pyrimidin-2-yl}isoquinoline

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsGENE REGULATION / Bromodomain / TAF1 / TBP / transcription / general transcription factor IID / TFIID / TF250 / non-BET / ATR / kinase

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