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TitleCrystal Structure of the Kinase Domain of Human Traf2- and Nck-Interacting Kinase with Wee1Chk1 Inhibitor
Journal, issue, pagesTo be Published
Publish dateFeb 26, 2010 (structure data deposition date)
AuthorsVollmar, M. / Alfano, I. / Shrestha, B. / Bray, J. / Muniz, J.R.C. / Roos, A. / Filippakopoulos, P. / Burgess-Brown, N. / Ugochukwu, E. / Gileadi, O. ...Vollmar, M. / Alfano, I. / Shrestha, B. / Bray, J. / Muniz, J.R.C. / Roos, A. / Filippakopoulos, P. / Burgess-Brown, N. / Ugochukwu, E. / Gileadi, O. / Phillips, C. / Mahajan, P. / Pike, A.C.W. / Fedorov, O. / Chaikuad, A. / von Delft, F. / Bountra, C. / Arrowsmith, C.H. / Weigelt, J. / Edwards, A. / Knapp, S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-2x7f:
Crystal structure of the kinase domain of human Traf2- and Nck- interacting Kinase with Wee1Chk1 inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-824:
9-HYDROXY-4-PHENYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / SERINE/THREONINE-PROTEIN KINASE / PHOSPHOPROTEIN / KINASE

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