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TitleCrystal structure of human Estrogen Receptor Alpha Ligand-Binding Domain in complex with a Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide and estrone ((8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15, 16-octahydro-6H-cyclopenta[a]phenanthren-17-one)
Journal, issue, pagesTo be Published
Publish dateMay 28, 2009 (structure data deposition date)
AuthorsRajan, S.S. / Kim, Y. / Vanek, K. / Joachimiak, A. / Greene, G.L.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.33 Å
Structure data

PDB-3hm1:
Crystal structure of human Estrogen Receptor Alpha Ligand-Binding Domain in complex with a Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide and estrone ((8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one)
Method: X-RAY DIFFRACTION / Resolution: 2.33 Å

Chemicals

ChemComp-J3Z:
(9beta,13alpha)-3-hydroxyestra-1,3,5(10)-trien-17-one

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / estrogen receptor / LBD / GRIP peptide / estrone / Alternative splicing / DNA-binding / Glycoprotein / Lipid-binding / Metal-binding / Nucleus / Phosphoprotein / Polymorphism / Receptor / Steroid-binding / Transcription regulation / Zinc / Zinc-finger / Activator / HORMONE / NUCLEAR RECEPTOR

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