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TitleCrystal structure of mouse CARM1 in complex with inhibitor SA0678
Journal, issue, pagesTo Be Published
Publish dateApr 27, 2017 (structure data deposition date)
AuthorsCura, V. / Marechal, N. / Mailliot, J. / Troffer-Charlier, N. / Wurtz, J.M. / Bonnefond, L. / Cavarelli, J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.25 Å
Structure data

PDB-5ntc:
Crystal structure of mouse CARM1 in complex with inhibitor SA0678
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-DXE:
1,2-DIMETHOXYETHANE

ChemComp-M2M:
1-METHOXY-2-(2-METHOXYETHOXY)ETHANE

ChemComp-B3P:
2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-6L7:
[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-(2-azaniumylethyl)-[(3~{S})-3-azaniumyl-4-oxidanyl-4-oxidanylidene-butyl]azanium

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsTRANSFERASE / PROTEIN ARGININE METHYLTRANSFERASE / CATALYTIC DOMAIN / CHROMATIN REGULATOR / MRNA PROCESSING / MRNA SPLICING / NUCLEUS / S-ADENOSYL-L-METHIONINE / TRANSCRIPTION / TRANSCRIPTION REGULATION

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