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-Structure paper
Title | Structural and molecular homogeneity of ATTRv-T60A amyloid fibrils across patients and organs |
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Journal, issue, pages | Structure, Year 2025 |
Publish date | Aug 8, 2024 (structure data deposition date) |
![]() | Fernandez-Ramirez MDC / Nguyen BA / Afrin S / Singh V / Evers B / Shelton JM / Escobar CL / Bassett P / Wang L / Pekala M ...Fernandez-Ramirez MDC / Nguyen BA / Afrin S / Singh V / Evers B / Shelton JM / Escobar CL / Bassett P / Wang L / Pekala M / Ahmed Y / Cabrera Hernandez LO / Pedretti R / Singh P / Canepa J / Wosztyl A / Li Y / Boyer DR / Cao Q / Saelices L |
![]() | ![]() |
Methods | EM (helical sym.) |
Resolution | 2.98 - 4.64 Å |
Structure data | EMDB-46479, PDB-9d21: EMDB-46481, PDB-9d23: EMDB-46482, PDB-9d24: EMDB-46487, PDB-9d27: EMDB-46495, PDB-9d2g: ![]() EMDB-46496: Cryo-EM structure of amyloid fibril extracted from heart of a variant ATTR T60A amyloidosis patient 3 |
Source |
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![]() | PROTEIN FIBRIL / Transthyretin / Amyloidosis / ATTR / Cardiac / Thyroid / Kidney / liver |