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TitleDiscovery of a Small Molecule ITK and Pan-TRK Kinase Inhibitor (PF-07245303) for the Potential Topical Treatment of Atopic Dermatitis
Journal, issue, pagesTo Be Published
Publish dateMar 24, 2025 (structure data deposition date)
AuthorsLiu, S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.348 Å
Structure data

PDB-9nwx:
Discovery of a Small Molecule ITK and Pan-TRK Kinase Inhibitor (PF-07245303) for the Potential Topical Treatment of Atopic Dermatitis
Method: X-RAY DIFFRACTION / Resolution: 1.348 Å

Chemicals

PDB-1b66:
6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / kinase / inhibitor / Atopic Dermatitis

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