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Structure paper

TitlehPDE4D2 structure with inhibitor NPD-656
Journal, issue, pagesTo be published
Publish dateSep 7, 2020 (structure data deposition date)
AuthorsSingh, A.K. / Brown, D.G.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.19 Å
Structure data

PDB-7ab9:
Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-656
Method: X-RAY DIFFRACTION / Resolution: 2.19 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-QWZ:
1-cycloheptyl-3-{4-methoxy-3-[2-(4-methoxyphenyl)ethoxy]phenyl}-4,4-dimethyl-4,5-dihydro-1H-pyrazol-5-one

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Phosphodiesterase / cAMP hydrolysis / alternative splicing

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