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-Structure paper
Title | Regio- and diastereoselective hydroxylation of steroids using P450-BM3: Readdressing the numbers problem in directed evolution |
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Journal, issue, pages | To Be Published |
Publish date | Jul 12, 2017 (structure data deposition date) |
![]() | Acevedo-Rocha, C.G. / Gamble, C. / Lonsdale, R. / Li, A. / Nett, N. / Hoebenreich, S. / Lingnau, J. / Wirtz, C. / Fares, C. / Hinrichs, H. ...Acevedo-Rocha, C.G. / Gamble, C. / Lonsdale, R. / Li, A. / Nett, N. / Hoebenreich, S. / Lingnau, J. / Wirtz, C. / Fares, C. / Hinrichs, H. / Deege, A. / Mulholland, A.J. / Nov, Y. / Leys, D. / Munro, A.W. / Reetz, M.T. |
![]() | Search PubMed |
Methods | X-ray diffraction |
Resolution | 2.09 Å |
Structure data | ![]() PDB-5og9: |
Chemicals | ![]() ChemComp-HEM: ![]() ChemComp-ZN: ![]() ChemComp-TES: ![]() ChemComp-CL: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE / cytochrome P450 / testosterone / laboratory evolution / hydroxylation / steroids |