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TitlePyrrolo[2,3-b]pyridines Inhibit the Checkpoint Kinase Chk1
Journal, issue, pagesTo be Published
Publish dateJun 10, 2005 (structure data deposition date)
AuthorsStavenger, R.A. / Zhao, B. / Zhou, B.-B.S. / Brown, M.J. / Lee, D. / Holt, D.A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-1zys:
Co-crystal structure of Checkpoint Kinase Chk1 with a pyrrolo-pyridine inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-199:
N-{5-[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]-1H-PYRROLO[2,3-B]PYRIDIN-3-YL}NICOTINAMIDE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / TRANSFERASE / Chk1; Crystal structure

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