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TitleCrystal structure of Human TEAD2 in complex with Cobimetinib
Journal, issue, pagesTo Be Published
Publish dateFeb 26, 2024 (structure data deposition date)
AuthorsHe, X.J. / Hu, L.Q. / Wu, M.Y.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.71 Å
Structure data

PDB-8ygq:
Crystal structure of Human TEAD2 in complex with Cobimetinib
Method: X-RAY DIFFRACTION / Resolution: 2.71 Å

Chemicals

ChemComp-PLM:
PALMITIC ACID

ChemComp-EUI:
[3,4-BIS(FLUORANYL)-2-[(2-FLUORANYL-4-IODANYL-PHENYL)AMINO]PHENYL]-[3-OXIDANYL-3-[(2S)-PIPERIDIN-2-YL]AZETIDIN-1-YL]METHANONE / medication, anticancer, inhibitor*YM

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Hippo pathway / TEAD Inhibitor

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