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TitleManuscript in preparation
Journal, issue, pagesTo Be Published
Publish dateJun 26, 2024 (structure data deposition date)
AuthorsIyer KA / Kobayashi T / Murayama T / Samso M
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.23 - 3.34 Å
Structure data

EMDB-45493: Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6, nanodisc and inhibitor dantrolene in the absence of calcium
Method: EM (single particle) / Resolution: 3.34 Å

45585

9cgq

EMDB-45585, PDB-9cgq:
Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6, nanodisc and inhibitor dantrolene in the presence of activating calcium
Method: EM (single particle) / Resolution: 3.23 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-CA:
Unknown entry


ChemComp, No image

ChemComp-U1C:
Unknown entry

Source
  • oryctolagus cuniculus (rabbit)
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / Ryanodine receptor / Calcium channel / Mutation / Y523S / RyR1 / dantrolene

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