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TitleSimultaneous inhibition of anti-coagulation and inflammation: Crystal structure of phospholipase A2 complexed with indomethacin at 1.4 A resolution reveals the presence of the new common ligand binding site
Journal, issue, pagesTo be Published
Publish dateDec 29, 2008 (structure data deposition date)
AuthorsSingh, N. / Prem Kumar, R. / Sharma, S. / Kaur, P. / Singh, T.P.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.4 Å
Structure data

PDB-3fo7:
Simultaneous inhibition of anti-coagulation and inflammation: Crystal structure of phospholipase A2 complexed with indomethacin at 1.4 A resolution reveals the presence of the new common ligand binding site
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-IMN:
INDOMETHACIN / medication*YM

ChemComp-HOH:
WATER

Source
  • daboia russelli pulchella (snake)
KeywordsHYDROLASE / PLA2 / Anti-inflammatory / Anti-coagulant / Indomethacin

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