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-Structure paper
Title | Discovery of 3H-benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective and Orally Bioavailable Pim Kinases Inhibitors |
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Journal, issue, pages | TO BE PUBLISHED |
Publish date | Sep 21, 2009 (structure data deposition date) |
![]() | Tao, Z.F. / Hasvold, L. / Leverson, J. / Han, E. / Guan, R. / Johson, E.F. / Stoll, V.S. / Stewart, K.D. / Stamper, G. / Soni, N. |
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Methods | X-ray diffraction |
Resolution | 2.1 - 2.8 Å |
Structure data | ![]() PDB-3jxw: ![]() PDB-3jy0: ![]() PDB-3jya: |
Chemicals | ![]() ChemComp-LXG: ![]() ChemComp-LYG: ![]() ChemComp-LWG: |
Source |
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![]() | TRANSFERASE / Pim-1 / Alternative initiation / ATP-binding / Cell membrane / Cytoplasm / Kinase / Manganese / Membrane / Metal-binding / Nucleotide-binding / Nucleus / Phosphoprotein / Polymorphism / Proto-oncogene / Serine/threonine-protein kinase |