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Structure paper

TitleInhibitor peptides against Mcl-1 containing non-natural amino acids show potent apoptotic response.
Journal, issue, pagesTo Be Published
Publish dateSep 10, 2019 (structure data deposition date)
AuthorsMandal, T. / Grant, R.A. / Keating, A.E.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.552 - 2.1 Å
Structure data

PDB-6ua3:
Human Mcl-1 in complex with a modified Bim BH3 peptide
Method: X-RAY DIFFRACTION / Resolution: 1.552 Å

PDB-6uab:
Human Mcl-1 in complex with a modified unnatural Bim BH3 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-ADM:
ADAMANTANE

Source
  • homo sapiens (human)
KeywordsPEPTIDE BINDING PROTEIN/Inhibitor / Inhibitor / PEPTIDE BINDING PROTEIN / PEPTIDE BINDING PROTEIN-Inhibitor complex

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