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TitleThe X-ray Crystal Structure of PCSK9 in Complex with the LDL receptor
Journal, issue, pagesTo be Published
Publish dateMar 2, 2010 (structure data deposition date)
AuthorsLi, J. / Gavigan, J.A. / Zheng, G. / Huang, W. / Yowe, D. / Geisse, S. / Harris, J.L. / Lesley, S.A. / Spraggon, G.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution7.01 Å
Structure data

PDB-3m0c:
The X-ray Crystal Structure of PCSK9 in Complex with the LDL receptor
Method: X-RAY DIFFRACTION / Resolution: 7.01 Å

Chemicals

ChemComp-CA:
Unknown entry

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / PROTEIN COMPLEX / BETA PROPELLER / CHOLESTEROL CLEARANCE / PCSK9 / LDLR / Autocatalytic cleavage / Cholesterol metabolism / Disease mutation / Disulfide bond / Glycoprotein / Hydrolase / Lipid metabolism / Phosphoprotein / Protease / Secreted / Serine protease / Steroid metabolism / Zymogen / Coated pit / EGF-like domain / Endocytosis / Host-virus interaction / LDL / Lipid transport / Membrane / Receptor / Transmembrane / Transport

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