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TitleStructural Definition of a Novel Nanobody Binding Site specifically targeting the MERS-CoV RBD Core-Domain with Neutralizing Capacity
Journal, issue, pagesTo Be Published
Publish dateFeb 13, 2023 (structure data deposition date)
AuthorsIdoudi, F. / Wang, R. / Tian, L. / Zhang, L. / Wang, X.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.901 - 3.59 Å
Structure data

PDB-8idi:
Crystal structure of nanobody VHH-T71 with MERS-CoV RBD
Method: X-RAY DIFFRACTION / Resolution: 1.901 Å

PDB-8idm:
Crystal structure of nanobody VHH-227 with nanobody VHH-T71 and MERS-CoV RBD
Method: X-RAY DIFFRACTION / Resolution: 3.59 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • camelus dromedarius (Arabian camel)
  • middle east respiratory syndrome-related coronavirus
KeywordsVIRAL PROTEIN / MERS-CoV / nanobody / VIRAL PROTEIN-IMMUNE SYSTEM complex

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