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Structure paper

TitleCrystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A048
Journal, issue, pagesTO BE PUBLISHED
Publish dateOct 17, 2014 (structure data deposition date)
AuthorsZhu, L. / Ren, X. / Zhu, J. / Li, H.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-4rli:
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A048
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-ORO:
OROTIC ACID

ChemComp-3SH:
ethyl 2-[(3-chloro-4-methylphenyl)amino]-4-phenyl-1,3-thiazole-5-carboxylate

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
Keywordsoxidoreductase/oxidoreductase inhibitor / oxidoreductase / FMN binding / mitochondria inner membrane / inner membrane / oxidoreductase-oxidoreductase inhibitor complex

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