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Author
Journal
IF

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Structure paper

TitleThe spontaneous base substitution mechanisms of human DNA polymerase beta
Journal, issue, pagesTo Be Published
Publish dateMay 3, 2014 (structure data deposition date)
AuthorsKoag, M.C. / Lee, S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.15 - 2.6 Å
Structure data

PDB-4pgy:
Structure of human DNA polymerase beta complexed with a nicked DNA containing a GT at N-1 position and GC at N position
Method: X-RAY DIFFRACTION / Resolution: 2.26 Å

PDB-4ph5:
Structure of human DNA polymerase beta complexed with a nicked DNA containing a AC at N-1 position and GC at N position
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

PDB-4phe:
Structure of human DNA polymerase beta complexed with T in the template base paired with incoming non-hydrolyzable GTP
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-4php:
Structure of human DNA polymerase beta complexed with T in the template base paired with incoming non-hydrolyzable GTP and MANGANESE
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-XG4:
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine

ChemComp-MN:
Unknown entry

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsTransferase / Lyase/DNA / human DNA polymerase beta / nucleotidyl transfer / Lyase-DNA complex / nucleotidyl trnasfer

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