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Structure paper

TitleComprehensive structural survey of DNA double-strand break synapsis by DNA Polymerase Lambda
Journal, issue, pagesNot Published
Publish dateMar 10, 2021 (structure data deposition date)
AuthorsKaminski, A.M. / Bebenek, K. / Kunkel, T.A. / Pedersen, L.C.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.7 - 2.65 Å
Structure data

PDB-7m08:
Post-catalytic nicked complex of DNA Polymerase Lambda with bound 1-nt gapped SSB substrate and incoming dUMPNPP
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-7m0c:
Post-catalytic nicked complex of DNA Polymerase Lambda with bound mismatched DSB substrate
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

ChemComp-PPV:
PYROPHOSPHATE

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsTRANSFERASE / Nonhomologous end-joining / Base Excision Repair

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