タイトル | Dimeric state and novel nucleotide-binding pocket drive CpAgo-mediated DNA cleavage |
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ジャーナル・号・ページ | To Be Published |
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掲載日 | 2024年9月9日 (構造データの登録日) |
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著者 | Liu Y / Li S / Zhang K |
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リンク | PubMedで検索 |
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手法 | EM (単粒子) |
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解像度 | 2.86 - 3.81 Å |
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構造データ | EMDB-61474, PDB-9jh7: Cryo-EM structure of CpAgo in complex with the 5'-P guide DNA. 手法: EM (単粒子) / 解像度: 3.4 Å EMDB-61475, PDB-9jh8: Cryo-EM structure of CpAgo_gDNA-tg_ssDNA monomeric ternary complex 手法: EM (単粒子) / 解像度: 3.81 Å EMDB-61476, PDB-9jh9: Cryo-EM structure of CpAgo_gDNA-tg_ssDNA dimeric ternary complex 手法: EM (単粒子) / 解像度: 3.42 Å EMDB-61485, PDB-9jhk: Cryo-EM structure of CpAgo_gDNA-tg_dsDNA monomeric ternary complex 手法: EM (単粒子) / 解像度: 3.42 Å EMDB-61486, PDB-9jhl: Cryo-EM structure of CpAgo_gDNA-tg_dsDNA dimeric ternary complex 手法: EM (単粒子) / 解像度: 2.86 Å EMDB-61487, PDB-9jhm: Cryo-EM structure of CpAgo_gDNA-tg_bubble_dsDNA monomeric ternary complex 手法: EM (単粒子) / 解像度: 3.2 Å EMDB-61488, PDB-9jhn: Cryo-EM structure of CpAgo_gDNA-tg_bubble_dsDNA dimeric ternary complex 手法: EM (単粒子) / 解像度: 3.0 Å |
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化合物 | |
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由来 |  clostridium perfringens (ウェルシュ菌)- synthetic construct (人工物)
clostridium perfringenosum (バクテリア)
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キーワード | DNA BINDING PROTEIN/DNA / pAgos / nucleotide-binding pocket / PAZ / cryo-EM / DNA BINDING PROTEIN / DNA BINDING PROTEIN-DNA complex / dimerization |
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