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Structure paper

TitleTemperature Gradient Structures of Oncogenic KRAS G12C Mutants
Journal, issue, pagesTo Be Published
Publish dateAug 18, 2023 (structure data deposition date)
AuthorsDeck, S.L. / Xu, M. / Aplin, C. / Milano, S.K.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.04 - 1.43 Å
Structure data

PDB-8tvk:
KRAS 1-169 G12C Mutant at 100k
Method: X-RAY DIFFRACTION / Resolution: 1.04 Å

PDB-8txj:
KRAS 1-169 G12C Mutant at 277k
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-8txk:
KRAS 1-169 G12C Mutant at 240k
Method: X-RAY DIFFRACTION / Resolution: 1.38 Å

PDB-8ty2:
KRAS 1-169 G12C Mutant at 293k
Method: X-RAY DIFFRACTION / Resolution: 1.41 Å

PDB-8ty8:
KRAS 1-169 G12C Mutant at 310k
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-8ty9:
KRAS 1-169 G12C Mutant at 313k
Method: X-RAY DIFFRACTION / Resolution: 1.43 Å

Chemicals

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / GTPase

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