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-Structure paper
Title | Human Aldose Reductase Mutant A299G/L300G in Complex with a Ligand with an IDD Structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid) |
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Journal, issue, pages | To Be Published |
Publish date | Sep 16, 2022 (structure data deposition date) |
![]() | Hubert, L.-S. / Heine, A. / Klebe, G. / Scheer, F. |
![]() | Search PubMed |
Methods | X-ray diffraction |
Resolution | 0.96 Å |
Structure data | ![]() PDB-8b3r: |
Chemicals | ![]() ChemComp-NAP: ![]() ChemComp-30L: ![]() ChemComp-CIT: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE / human Aldose Reductase / hAR / Aldo-keto-reductase / A299G/L300G mutant / IDD_06 / nadp+ / diabetes / ligand in transient pocket / no flip |