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TitleCrystal structure of human SIRT5 in complex with diazirine inhibitor 9
Journal, issue, pagesTo Be Published
Publish dateMar 1, 2022 (structure data deposition date)
AuthorsLi, G.-B. / Deng, J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.56 Å
Structure data

PDB-7x3p:
Crystal structure of human SIRT5 in complex with diazirine inhibitor 9
Method: X-RAY DIFFRACTION / Resolution: 1.56 Å

Chemicals

ChemComp-8VG:
5-[[(5~{S})-6-[[(1~{S})-1-(4-hydroxyphenyl)-2-oxidanylidene-2-(prop-2-ynylamino)ethyl]amino]-6-oxidanylidene-5-[[4-[3-(trifluoromethyl)-1,2-diazirin-3-yl]phenyl]carbonylamino]hexyl]amino]-5-sulfanylidene-pentanoic acid

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / inhibitor / complex / hydrolase / HYDROLASE-HYDROLASE INHIBITOR complex

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