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TitleStructural basis of STING binding with phospholipid PI4P and activation by a molecule targeting a new pocket
Journal, issue, pagesTo Be Published
Publish dateOct 9, 2024 (structure data deposition date)
AuthorsHan J / Zhang S / Hou Y / Wang Y / Zhang Z / Yang J / Chen K / Liu X / Zhang C
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.71 Å
Structure data

61849

9jw6

EMDB-61849, PDB-9jw6:
STING bound with a novel small molecule agonist
Method: EM (single particle) / Resolution: 2.71 Å

Chemicals

PDB-1edl:
STAPHYLOCOCCAL PROTEIN A E-DOMAIN (-60), NMR, 22 STRUCTURES

PDB-1eer:
CRYSTAL STRUCTURE OF HUMAN ERYTHROPOIETIN COMPLEXED TO ITS RECEPTOR AT 1.9 ANGSTROMS

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / endoplasmic reticulum / cyclic dinucleotides / signaling / adaptor protein

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