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Structure paper

TitleStructural insights into IgA recognition by M64 peptidases
Journal, issue, pagesTo Be Published
Publish dateMar 6, 2025 (structure data deposition date)
AuthorsMarquez-Monino, M.A. / Martinez Gascuena, A. / Azzam, T. / Pesson, A. / Manzanares-Gomez, A. / Aguillo-Urarte, M. / Brown, T.T. / Montero, A. / Lood, R. / Naegali, A. ...Marquez-Monino, M.A. / Martinez Gascuena, A. / Azzam, T. / Pesson, A. / Manzanares-Gomez, A. / Aguillo-Urarte, M. / Brown, T.T. / Montero, A. / Lood, R. / Naegali, A. / Du, J.J. / Connell, S.R. / Sastre, D.E. / Sundberg, E.J. / Trastoy, B.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.94 - 2 Å
Structure data

PDB-9qdh:
Crystal structure of IgA protease (323-878) from Thomasclavelia ramosa
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-9qdi:
Crystal structure of BF3526 peptidase from Bacteroides fragilis in complex with a peptide
Method: X-RAY DIFFRACTION / Resolution: 1.94 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-K:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-POL:
N-PROPANOL

ChemComp-BU1:
1,4-BUTANEDIOL

ChemComp-HEZ:
HEXANE-1,6-DIOL

Source
  • thomasclavelia ramosa (bacteria)
  • bacteroides fragilis nctc 9343 (bacteria)
  • synthetic construct (others)
KeywordsHYDROLASE / IgA protease / peptidase / protease / IgA-P / M64 / metallopeptidase / metalloprotease / antibody / Ig / IgA / Thomasclavelia / metzincin / nephropathy / IgAN / hinge / BF3526 / Bacteroides / complex / substrate / product

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