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TitleCrystal structure of the human METTL3-METTL14 complex with compound T180
Journal, issue, pagesTo Be Published
Publish dateMar 31, 2021 (structure data deposition date)
AuthorsBedi, R.K. / Huang, D. / Caflisch, A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-7o2x:
Crystal structure of the human METTL3-METTL14 complex with compound T180
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-V0B:
N-[(6-methylimidazo[1,2-a]pyridin-2-yl)methyl]-4-oxidanylidene-pyrido[1,2-a]pyrimidine-2-carboxamide

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / METTL3 / Inhibitor / complex

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