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TitleHuman p38 ALPHA MAPK:MW164 pyridazine inhibitor complex
Journal, issue, pagesTo Be Published
Publish dateSep 11, 2025 (structure data deposition date)
AuthorsBrunzelle, J.S. / Shuvalova, L. / Roy, S.M. / Watterson, D.M.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.97 Å
Structure data

PDB-9y8b:
Human p38 ALPHA MAPK:MW164 pyridazine inhibitor complex
Method: X-RAY DIFFRACTION / Resolution: 1.97 Å

Chemicals

ChemComp-GG5:
4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE

PDB-1ctd:
DETERMINATION OF THE SOLUTION STRUCTURE OF A SYNTHETIC TWO-SITE CALCIUM-BINDING HOMODIMERIC PROTEIN DOMAIN BY NMR SPECTROSCOPY

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / SERINE/THREONINE-PROTEIN KINASE / PROTEIN KINASE DOMAIN / TRANSFERASE / ATP BINDING / PHOSPHORYLATION / CYTOSOL / TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX

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