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Structure paper

TitleHEXAPEPTIDE MIMETICS OF LEDGF IN COMPLEX WITH HIV-1 INTEGRASE
Journal, issue, pagesTo Be Published
Publish dateFeb 7, 2015 (structure data deposition date)
AuthorsNorthfield, S.E. / Wielens, J. / Headey, S.J. / Mulcair, M. / Scanlon, M.J. / Parker, M.W. / Thompson, P.E. / Chalmers, D.K.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.93 - 2.3 Å
Structure data

PDB-4y1c:
Cyclic hexapeptide cyc[NdPopPKID] in complex with HIV-1 integrase core domain
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-4y1d:
Cyclic hexapeptide cyc[NdPopPKID] in complex with HIV-1 integrase core domain
Method: X-RAY DIFFRACTION / Resolution: 1.93 Å

Chemicals

ChemComp-CD:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

Source
  • human immunodeficiency virus 1
  • synthetic construct (others)
KeywordsTRANSFERASE/TRANSFERASE BINDING PROTEIN / DNA INTEGRATION / AIDS / ENDONUCLEASE / POLYNUCLEOTIDYL TRANSFERASE / DNA BINDING / VIRAL PROTEIN / RNASEH / LEDGF / LENS EPITHELIUM DERIVED GROWTH FACTOR / VIRAL PROTEIN-PEPTIDE COMPLEX / TRANSFERASE-TRANSFERASE BINDING PROTEIN complex

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