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TitleCrystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And AT-001
Journal, issue, pagesTo Be Published
Publish dateDec 13, 2022 (structure data deposition date)
AuthorsArenas, R. / Wilson, D.K.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.62 Å
Structure data

PDB-8fh5:
Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And AT-001
Method: X-RAY DIFFRACTION / Resolution: 1.62 Å

Chemicals

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-XXQ:
(8-oxo-7-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-7,8-dihydropyrazino[2,3-d]pyridazin-5-yl)acetic acid

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / COMPLEX / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX / OXIDOREDUCTASE

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