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TitleA Parasite Coat Protein Binds Suramin to Confer Drug Resistance
Journal, issue, pagesNat Microbiol, Vol. 6, Page 392-400, Year 2021
Publish dateMay 30, 2020 (structure data deposition date)
AuthorsZeelen, J.P. / van Straaten, M. / Verdi, J. / Hempelmann, A. / Hashemi, H. / Perez, K. / Jeffrey, P.D. / Haelg, S. / Wiedemar, N. / Maeser, P. ...Zeelen, J.P. / van Straaten, M. / Verdi, J. / Hempelmann, A. / Hashemi, H. / Perez, K. / Jeffrey, P.D. / Haelg, S. / Wiedemar, N. / Maeser, P. / Papavasiliou, F.N. / Stebbins, C.E.
External linksNat Microbiol / Search PubMed
MethodsX-ray diffraction
Resolution1.21 Å
Structure data

PDB-6z7a:
Variant Surface Glycoprotein VSGsur
Method: X-RAY DIFFRACTION / Resolution: 1.21 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • trypanosoma brucei rhodesiense (eukaryote)
KeywordsMEMBRANE PROTEIN / Variant surface glycoprotein Suramin Trypanosomiasis Drug resistance Glycosylation

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