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TitleStructure-based discovery of inhibitors of the human SLC19A3
Journal, issue, pagesTo Be Published
Publish dateNov 28, 2024 (structure data deposition date)
AuthorsGabriel F / Windshuegel B / Loew C
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.35 Å
Structure data

52213

9hjd

EMDB-52213, PDB-9hjd:
Cryo-EM structure of domperidone-bound human SLC19A3 in inward-open state
Method: EM (single particle) / Resolution: 3.35 Å

Chemicals

PDB-1ivj:
Crystal Structure of Rat Hemeoxygenase-1 in Complex with Heme and Azide.

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
  • lama glama (llama)
KeywordsMEMBRANE PROTEIN / Thiamine transporter / drug interaction / thiamine deficiency

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