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Structure paper

TitleLRRK2 Roc domain RP (Ras-pocket) complexed to Divarasib
Journal, issue, pagesTo Be Published
Publish dateJun 10, 2024 (structure data deposition date)
AuthorsZhu, L.Y. / Shokat, K.M.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-9c76:
LRRK2 Roc domain RP (Ras-pocket) complexed to Divarasib
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-BR:
BROMIDE ION

ChemComp-MG:
Unknown entry

ChemComp-F:
FLUORIDE ION

PDB-1awr:
CYPA COMPLEXED WITH HAGPIA

ChemComp-IOD:
IODIDE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / GTPase / Complex / chemical biology / switch II

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