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TitleDiscovery of Novel LSD1 Inhibitors for the Treatment of Autosomal Dominant Polycystic Kidney Disease
Journal, issue, pagesTo Be Published
Publish dateMar 8, 2024 (structure data deposition date)
AuthorsJiang, H. / Tongchao, L. / Bing, X. / Zhiyan, D. / Danyan, C.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.83 Å
Structure data

PDB-8ym7:
Crystal structure of Lysine Specific Demethylase 1 (LSD1) with JH-45
Method: X-RAY DIFFRACTION / Resolution: 2.83 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

PDB-1lzj:
Glycosyltransferase B + UDP + H antigen acceptor

Source
  • homo sapiens (human)
KeywordsFLAVOPROTEIN / LSD1

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