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Structure paper

TitleStructure of c-Kit with allosteric inhibitor 3G8
Journal, issue, pagesTo Be Published
Publish dateAug 24, 2018 (structure data deposition date)
AuthorsWrasidlo, W.J. / Cheresh, D.A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.25 Å
Structure data

PDB-6hh1:
Structure of c-Kit with allosteric inhibitor 3G8
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-G4E:
~{N}-(2,3-dimethylphenyl)-5-(4-pyridin-4-yloxyphenyl)-4~{H}-1,2,4-triazol-3-amine

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / c-Kit / kinase / allosteric / inhibitor

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